Personally, I believe this investment is at an EXTREMELY risky juncture because we have no clue how good Lombardo is or what he's going to make happen.
On the other hand, unless Lombardo is a criminal, embezzler, or worse, his personal qualities will play a fairly small part in determining the future of ADXS.
The most significant variables are the science and clinical success. Most longs agree that those are in pretty good shape. In my view, that reduces the risk from "EXTREME" to reasonable, with a fair expectation of success.