Avastin is not anti tumor agent in many cancers and gbm is one of them. It just help with swelling and side effects from other medication cancer patients take. Avastin is like placebo in rgbm. The overall survival of avastin is dependent on number of patients and tumor size . Small amount of patients show 35% os after 12 month only because sample was small. In Bristol mayers trial the tumor was small in all patients so the mos was 10 months. Avastin is useless and a very good candidate to beat in rgbm
If you still think that timing of recruiting (august 15 to nay 16 first 50 ca, june 16 to august 16 another ca 78 and Sept 16 to Nov 16 another ca 126 and dec 16 the last 2 patients ) is an assumption you have not Been paying attention. Also timing of events is not an assumption as we know we have not reached the 189th event yet
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