Replies to post #1326 on Vascular Biogenics Ltd (VBLT)

[staccani]

Attached a few examples of interim efficacy analyses and what it implies in terms of statistical considerations. Not easy stuff


http://www.uta.fi/hes/dpph/materials/Interim_Analysis_BKSinha2011Sept.pdf

[Jumpinjackas]

Agree with you here. I've been part of trials, prepping data for DSMC.

They look for safety and INEFFCIENCY.
Meaning the trial will not continue if combo is causing more harm, dying sooner than Avastin only arm. But they are not doing any detailed analysis.