Replies to post #213820 on Biotech Values

[semi_infinite]

PLSE +24% on the private placement news. I would love to know what data the FDA asked for. On the PLSE website, they provide a summary of preclinical studies on the effect of electroporation on tumors and immune response. Could the FDA be asking for clinical data via randomised studies? It would be fantastic if it works but it seems a lot of work lays ahead to prove it.

http://www.pulsebiosciences.com/major-discoveries/

[linhdtu]

This may be of interest to you.

https://tinyurl.com/y9cwknql

"The new case involved a Frenchman whose brain damage, suffered in a car accident, left him completely unresponsive and unconscious, known as a vegetative state. He became minimally conscious, responding to some signals from the outside world, after a month of having his vagus nerve — which runs from the abdomen to the brain, where it has numerous connections to regions that the researchers call “a hot zone for conscious awareness” — stimulated with a device implanted in his chest.

Brain imaging and electrical recordings of brain activity (EEG) showed changes that likely account for his improvement, scientists led by Angela Sirigu of France’s National Center for Scientific Research reported in Current Biology.

UCLA psychologist Martin Monti, an expert on consciousness who has used ultrasound directed at the thalamus to awaken a coma patient, said the French study seemed solid but somewhat vague on how much the patient improved. “They just don’t make it very clear what exactly he recovered,” Monti said, such as “just some small sign of consciousness or [whether he] could, say, blink eyes in response to command.”

[semi_infinite]

plse - Quite a bounce, almost doubled, since news of 510K application withdrawal a month ago. Resubmittal with requested data must be a slam dunk.

[semi_infinite]

PLSE - Truly amazing run given the FDA issues. 10Q has section and comments about FDA risk but not much more offered on what soft tissue data the FDA asked for that caused prior management to withdrawal application. Duggan has replaced completely the prior management since. He now owns 36% of company. Is that the only reason the stock has rocketed from his $15 purchase price? Low float and illiquid options makes this highly volatile but I may give it a shot.

http://services.corporate-ir.net/SEC.Enhanced/SecCapsule.aspx?c=254359&fid=15283322

[semi_infinite]

AKAO - Since you are a Duggan fan, you may want to check out his purchase receipts. I have some and just found out today that he is an activist. Company PR's positive P1 data today on C-scape with not much reaction. PDUFA date expected in late Q2 on plazomicin.

http://investors.achaogen.com/secfiling.cfm?filingid=921895-17-2833&cik=1301501