we already know if b-om is as good as preliminary results leo will seek fast track. Not worried about a ph2b with b-up, because it will then be sought after by BP...as for K, we better pray that activating p53 doesn't catch fire with tumor shrinkage efficacy because the sciencesmiths of the world may have to give it a second look...lets not to forget about praying for P which aleady is in protective mode with the alpha and investigator bias groups, whose only results that we'll see is in January 18 imo, all imo