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biopharm

08/21/17 7:05 PM

#309418 RE: aikifredicist #309417

I would rather see Sean Parker get involved publicly with this ....maybe he misses the excitement of those paradigm shifting Napster days .....and Facebook.....etc

Leaving behind the legacy of splitting Big Pharma in half all while helping Billions of peoples immune system respond to optimal levels will no doubt make Parker Cancer Institute #1 ....

Memorial Sloan Kettering is the founding member of PCI and guess that tells all that Dr Jedd Wolchok has a role to play yet

PS: For those NASA fans out there I hear they are looking into exosomal type biomarkers and SINCE flipped is the #1 root that is suppressing the immune system.....hmmmmm.....

jakedogman1

08/21/17 8:22 PM

#309427 RE: aikifredicist #309417

could be but he has a significant investment in PPHM. and imo stafford has a somewhat fiduciary duty w/ pphm given his nominees for the BOD. so it could be win win... if bp intervenes it could be good as well... and maybe xencor actually has the skill sets and relationships with bp to get the ps platform off the bench... whatever stafford might be bringing to the party, it is better than the current cast of crooks imo...

jq1234

08/21/17 9:08 PM

#309429 RE: aikifredicist #309417

>> Could Stafford's prime motivation be to put bavi (or BB's) in Xencor's hands.


Why would Xencor want Bavi (or BB)? They have large number of clinical candidates based on their unique Fc engineering platform. You are not making this statement based on completely false claim on this board that Xencor is CAR-T company, are you? Xencor has bispecific mAbs, CAR-T competitor, they are not CAR-T. Look at the partners they have based on their Fc engineering platform. Bavi (or BB)? Only on this board!

eb0783

08/21/17 9:23 PM

#309431 RE: aikifredicist #309417

Thank you aikifredicist, that is exactly what we have been saying. Stafford "knows his way around developing the IP" but tells us ours has

been clinical failure
unsuccessful (repeatedly stated)
disappointing results
poor performance
evidence against bavituximab is clear
has not produced any statistically significant results
failed clinical development
squandering additional capital
high risk clinical development
profligate spending on risky clinical development
it is questionable whether any further spending on its development is warranted
must immediately cease all clinical development

So who is he trying to scam?? He has been invested (and on the board) in Xencor for over 18 years watching/overseeing --> "at Xencor.... they're relying on our proprietary XmAb Fc domains." But I do believe that bavi has its own Fc domain which, after bavi covers the PS and reduces the MDSCs by over 40%, turns on the immune system to attack the cancers (and viruses, and bacteria, and parasites, and, and, and) AND then makes the patient immune to future development/return of the same disease. I am convinced in my mind that Stafford is quite educated on these things, although he claims that our IP has "zero value." BEWARE. Stafford sounds like the people that Steinbeck wrote about in his THE PEARL who gave their valuation to the PEARL owner.