They have to grow organically. Various indexes have thresholds that must be maintained for a duration of time, or they lose their status. The thresholds are usually any where in the range of 1 to 5 dollars...again, depending on the institution. 3pps seems to be a target for a penny OTC, However, they usually surpass that significantly for buffer room in case the stock recedes. One more point. Up listing is relatively expensive, it is not free. The up listing fees are more expensive then CYDY has cash. I believe this is another reason for CYDY to hold out until the dust settles post Combo PE's.
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