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Scottwny

07/17/17 2:14 PM

#190639 RE: TheHound #190627

I understand this. I was originally commenting on the post that you reposted from another person, which said "To summarize: Prurisol met the primary endpoint (2 pt reduction) in 35% of ALL patients who received a 200mg dose per day."

The "ALL" was even capitalized as if to stress this factor. However, there are 7 people who were assigned to the 200mg arm that are not included in this percentage; therefore, I believe this statement is false (unless the company reported these 7 individuals did not take 200mg per day, but I don't recall ever seeing/hearing this).

I'm not trying to be difficult, but with a small sample size, I believe we need to be careful with how we analyze the data.

MinnieM

07/17/17 6:39 PM

#190687 RE: TheHound #190627

For the those that may not know:

ITT = Intent to Treat

PP = Per Protocol

PP is a subset of ITT

I realize most know this, but, I suspect there are a few that may not.