From their own PR announcing Patency-1 failure, the description was:
"PATENCY-1 evaluated the safety and efficacy of a single dose of vonapanitase in patients with chronic kidney disease (CKD) receiving or expecting to receive hemodialysis who underwent surgical creation of a radiocephalic arteriovenous fistula."
From their PR regarding Patency-2, the description is:
"PATENCY-2 is a multicenter, randomized, double-blind, placebo-controlled study expected to enroll 500 patients in the United States and Canada with chronic kidney disease (CKD) undergoing surgical creation of a radiocephalic arteriovenous fistula for hemodialysis."
Both trials investigated 30 ug vonapanitase. So if the dosing is the same, and the patient population is the same, why should Patency-2 provide different data?