Replies to post #102167 on PAO Group Inc (PAOG)

[Erbmanus]

Well thank you DrBerry! Good news for $NWAV :-D

[LCLiving]

$NWAV Agree Dr, great news for sure. We're in a Summer Market, so many people are on vacation, hence drop in postings on the hub. PAO Group is setting this up perfectly, and the Market will realize the value here soon enough.

[LCLiving]

$NWAV I especially liked this from the link-


Medical Marijuana Legalization and Prescription Opioid Use Outcomes

NIDA funded two recent studies that explored the relationship between marijuana legalization and adverse outcomes associated with prescription opioids. The first found an association between medical marijuana legalization and a reduction in overdose deaths from opioid pain relievers, an effect that strengthened in each year following the implementation of legislation.78 The population-based nature of this study does not establish a causal relationship or give evidence for changes in pain patient behavior.79,80

The second NIDA-funded study, a more detailed analysis by the RAND Corporation, showed that legally protected access to medical marijuana dispensaries is associated with lower levels of opioid prescribing, lower self-report of nonmedical prescription opioid use, lower treatment admissions for prescription opioid use disorders, and reduction in prescription opioid overdose deaths.81 Notably, the reduction in deaths was present only in states with dispensaries (not just medical marijuana laws) and was greater in states with active dispensaries.

Research into the effects of cannabis on opioid use in pain patients is limited, but data suggest that medical cannabis treatment may reduce the dose of opioids required for pain relief.82,83 In addition to its research portfolio on the roles of the cannabinoid and opioid systems in pain, NIDA is funding additional studies that will provide data relating to medical marijuana and opioids:

effects of access to medical marijuana on substance use, including nonmedical use of prescription opioids (project numbers DA031816-05, DA039293-01A1, DA037341-02, DA032693-04)
mental and physical functioning of a cohort of pain patients seeking medical marijuana treatment (DA033397-03)
the impact of medical marijuana policies on health outcomes (DA034067-03)

Another recent study analyzed Medicare prescription drug coverage data and found that availability of medical marijuana significantly reduced prescribing of medications used for conditions that medical marijuana can treat, including opioids for pain.84 Overall savings for all prescription drugs were estimated to be $165.2 million in 2013.

Though none of these studies are definitive, they cumulatively suggest that medical marijuana products may have a role in reducing the use of opioids needed to control pain. More research is needed to investigate this possibility.