When we're trying to come up with a good screening test for millions of people, anecdotal evidence should be avoided.
Everyone has a second cousin's great grandmother who was saved by a mammogram. Unfortunately, millions of other women are on the agonizing receiving end of a false positive, or worse, a false cancer diagnosis, with chemo, radiation, and surgery to boot. All for a cancer they never had.
PSA is similar. For every third cousin's grandfather who is saved by a PSA, millions undergo unnecessary biopsy and subsequent erectile dysfunction, incontinence, and pain.
Anecdotes have no place when you're involving millions of people.
My point with PPHM's vesicular exosome test is more nuanced. Yes, it certainly has benefits, and if you re-read my post, you'll see I support early detection multiple times, but early screening doesn't guarantee anything.
What if it means people get chemo earlier? OK, they'll probably just die earlier.
What about lifestyle changes? Can people REALLY change? Yes, if they're scared enough. Maybe PS exosomes can provide that fear.
Be careful what you wish for with modern medicine. You'll probably get it.
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