Near the end of the article it speaks of turning COLD tumours into HOT!
"Another issue being investigated is “hot” versus “cold” tumours. In this context, hot tumours are those with many aberrant proteins which are detectable by the host’s immune system, and checkpoint inhibitors have proven markedly useful in these cases. Determining whether the immune system can be primed in the case of cold tumours by killing some cancer cells, allowing dissemination of those proteins and then initiating checkpoint inhibitor therapy is also under investigation."
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