Peter, I fail to understand what you encompass in your use of the word 'That's". I was not concerned with LOXO's detection technology issues, like the mutations you mention. I suspect GRAIL will encounter the same problem with the mutations occurring in what it tries to detect and analyze.
I am more interested in Dr. Schroit's discovery at UTSW and how it might be commercialized, perhaps with the aid of PKI[one of PKI's personnel, Hoyt by name, appeared as an author on the follow-on ASCO Abstract/poster #11603]. An exosome with PS as a target on its outer surface will not mutate in a manner to escape detection, as a reading of his journal article and published patent application I earlier provided[in the 2nd link] will establish. I am as interested as you are in early detection & diagnosis of PC or OC.
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