How can u even think about taking a drug like avastin that all of the drug user never had a complete respond and mix it with a drug that had in the past full responders which are durable for over 6 years other words cancer was cured. It's the stupidest thing to do .even my cat won't mix these 2. There is a biological reason avastin never cause cr and vb111 does - it's not without a reason.