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Pepperchino

06/04/17 10:10 AM

#184076 RE: runninggirl2016 #184071

Definitive results showing P53 activation will be HUGE! The path we are taking to target OC is brilliant IMO. Once an MOA is shown/discovered, K will move front and center against the fight of OC and many many other studies by the lucky BP who happens to have the deepest pockets to acquire the rights. Game changer...

Blue Fin

06/04/17 10:17 AM

#184077 RE: runninggirl2016 #184071

Estimated Enrollment:
10
Actual Study Start Date:
February 9, 2017
Estimated Study Completion Date:
December 31, 2017
Estimated Primary Completion Date:
December 31, 2017 (Final data collection date for primary outcome measure)
Arms
Assigned Interventions
Experimental: Cohort 1
Kevetrin 250 mg/m2 IV per dose every other day (q.o.d.)/ 3 doses per week (750 mg/m2 per week), for 3 weeks (single cycle; total 9 doses) Follow-up For 3 weeks after Kevetrin treatment ends
Drug: Kevetrin
Kevetrin dose to associated cohort
Other Name: Cohort
Experimental: Cohort 2
Kevetrin 350 mg/m2 IV per dose every other day (q.o.d.)/ 3 doses per week (1050 mg/m2 per week), for 3 weeks (single cycle; total 9 doses) Follow-up For 3 weeks after Kevetrin treatment ends
Drug: Kevetrin
Kevetrin dose to associated cohort

https://clinicaltrials.gov/ct2/show/NCT03042702

scottsmith

06/04/17 10:58 AM

#184082 RE: runninggirl2016 #184071

Any more insight into when we can hope to see Prurisol results?