Replies to post #859 on Vascular Biogenics Ltd (VBLT)

[Doktornolittle]

As a true immunotherapy, VB-111, if effective, would likely be used in immunotherapy cocktails. In this case in cocktails for many indications.

Most chemotherapies work by chocking both the good and bad cells and hoping that the cancer dies before the good cells. It sometimes does because cancer is already more stressed due to vascularization not keeping up with cell growth, and metabolism being pushed to the limits. So adding a second effective chemotherapy is not necessarily an improvement because you are already dosing to the brink of cell death for the normal cells.

But you can keep adding immunotherapies to a cocktail if they individually do not harm the patient. Very different from a chemotherapy. Maybe less $ per indication, but these cocktails may become pervasive across many indications and their true value could be far higher than the chemotherapies if they combine to effect a cure where chemotherapy only prolonged life while reducing quality of life.

If VB-111 is effective and has no side effects.

[memeil26]

I don't think that the patients had the privilege of what treatment they get upon disease progression