Let's put things into perspective. Volume is a relative term to the company we are analyzing. A company such as CYDY will never have the high volume of a low volume day for a DOW 30 company.
What is significant, as low as the numbers are in terms of shares or the dollar volume of those shares traded is the differential between the running average volume and either spikes up or really low volume days when there is no interest in buying or selling.
For someone bullish, we love seeing a spike in volume on up days or a decrease in volume on down days.
On the other hand, people with short positions get agitated on days when the volume spikes up as well as the price, regardless of what the volume is compared to the large cap stocks.