Replies to post #16129 on Ayala Pharmaceuticals Inc (ADXS)

[sandman44]

ADXS is where it's at for one reason ( GREED) in due time the tables will turn and ( GREEDS ) ruling days will come to an abrupt halt. ;) ADXS

[ignatiusrielly35]

True, Meisha. However, I would hazard to guess that the optimal dosing in PIII will show in excess of 50% 12-month. Which, in addition to the superior safety profile over Avastin, would be a 67%+ improvement over the SOC.

[taketobank]

Women are taking bevacizumab because i don't think they have a choice. Given a choice I believe most women would choose axal. Similar or better effectiveness without the harsh side effects. Hopefully less chance of recurrence.

The phase 3 trial will allow us to give the drug earlier so I'm hoping it will blow bev out of the water. Hoping.

[shub]

Well put Meishairwin...thanks.
For years on end folks on the boards have been insisting that the SP is absurdly low and that a huge deal or a massive buy out will happen in the immediate future.
I've sunk too many $ in this for longer than makes any economic sense, even by my very long term standards.
The science has been very appealing all along, but progress has been glacial and management is a bit better now, but hardly good.
In the past, when we showed results like the recent GOG trial, the SP would soar dramatically. This time we sank and kept sinking.
Note that we have never had a negative clinical trial result that i know of !

It's beginning to look like we are going to have to pull off a big, properly controlled, Ph 2 trial with splendid results followed by FDA approval
before we get any real respect.
I'm getting old waiting.