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Android 2-73

03/16/17 4:05 PM

#1018 RE: Extremist223 #1016

that makes sense logically.

postmeridiem

03/16/17 6:46 PM

#1024 RE: Extremist223 #1016

During the presentation, TGTX compared TG-1101 to ocrelizumab (Ocrevus), which is currently in use for b-cell depletion in MS. TGTX did not claim a safety advantage or an efficacy advantage over ocrelizumab. They said their advantages will be convenience and cost if the drug is approved.

Adverse events in CAR-T cancer trials are not relevant to the MS trial.