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wcopeland

02/25/17 9:38 AM

#647 RE: Prana1 #646

1. To be clear Prana1, VBLT "completed enrollment" for Ph3 rGBM. You mention several times that the "trial was completed", and so I feel that it worth clarifying.

2. I agree, the fact that so many doctors believe in (and recommend) VB111 is amazing and should not be overlooked.

3. VBLT did not really change the trial structure, they changed the analysis protocol. Maybe a subtle difference, but it is not like they changed dosing, scheduling, enrollment, etc. - things that are structural elements of the GLOBE trial. Instead, they changed the requirements for when interim and final analyses are triggered. Take a look at this board starting around Post #545 (gr8db8's comments) to track discussion about this point.

4. A bit of your confusion may stem from being newer to this investment? Take a look at some of the press releases on VBL's IR website to get a better historical perspective.