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misiu143

02/20/17 10:52 AM

#11100 RE: fred198484 #11098

I know a lot about Ibalizumab , I don't think it is a competition to Pro 140.

It is CD4 entry inhibitor , so some patients with out CCR5 Pro 140 is not working anyway.
So far IV will be approve but im or sc is early. For IV every 2 weeks patient need to go to the hospital or clinic.

They used Ibalizumab as monotherapy ONLY in P1 for HIV negative as a prevention few years ago , otherwise is use ONLY as adjunct with HAART ,

I e-mailed Dr Chen few times in the past ( I think this is his name ) and according to him they not planning to use as monotherapy,

Also couple of months ago I read that they have only 36% patient with IV treatment with Viral Load <50copis/mill, maybe now little better I dont know.

But for All patients benefit I wish well to both medication.



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goldenisla

02/20/17 12:17 PM

#11103 RE: fred198484 #11098

I would say that ibalzumad is definitely competition as far as adjunct therapy goes. And they have received orphan drug and breakthrough therapy designation so it obviously works, and the fda likes it. It does have minor side effects though... nausea, headaches, and while you do need an iv it is only once every 2 weeks I think?
When pro 140 works it seems to be stronger.... in that it causes a greater reduction in viral load. No side effects at all, and pro 140 has show it can work all by itself ... which ibalzumad has not shown, and they seem to be only targeting people who have failed other hiv therapies.
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5TOP

02/20/17 1:27 PM

#11106 RE: fred198484 #11098

Welcome back Fred. Yes we are all still aware of Ibalizumab. As we were when we had this very same discussion with you back in August. Let me save you some time and effort. Here are your posts from 6 months ago:

#5640 http://investorshub.advfn.com/boards/read_msg.aspx?message_id=124822407

#5645 http://investorshub.advfn.com/boards/read_msg.aspx?message_id=124825605

#5647 http://investorshub.advfn.com/boards/read_msg.aspx?message_id=124825651

#5668 http://investorshub.advfn.com/boards/read_msg.aspx?message_id=124856294

And if you need to refresh your memory, the replies to each of your posts can be viewed from each message.