I know a lot about Ibalizumab , I don't think it is a competition to Pro 140.
It is CD4 entry inhibitor , so some patients with out CCR5 Pro 140 is not working anyway.
So far IV will be approve but im or sc is early. For IV every 2 weeks patient need to go to the hospital or clinic.
They used Ibalizumab as monotherapy ONLY in P1 for HIV negative as a prevention few years ago , otherwise is use ONLY as adjunct with HAART ,
I e-mailed Dr Chen few times in the past ( I think this is his name ) and according to him they not planning to use as monotherapy,
Also couple of months ago I read that they have only 36% patient with IV treatment with Viral Load <50copis/mill, maybe now little better I dont know.
But for All patients benefit I wish well to both medication.