Pharma companies have spent literally billions of dollars chasing a theory that has proven to be wrong ("amyloid causes Alzheimer's"). And Dr. Alkon has explained in scientific detail why Amyloid plaques are only one part of the problem. Further he has explained how PKC Epsilon (Bryostatin) plays a role in many aspects of a healthy memory--PKC Epsilon is multi-modal.
His analysis is backed up with years of research, meticulously analyzing healthy and diseased cadaver brains, performing myriad animal tests with Bryostatin, and culminating in what we know today: Bryostatin was administered to severe Alzheimer's compassionate-use patients that were remarkably improved by Bryostatin.
No other trial drug has ever had a comparable remarkable effect on severe AD patients.
While Bryostatin may not be the ultimate solution, there's a lot of evidence that suggests it has a decent shot at working, on its own merits without any other drugs. There is risk, of course, but everyone has to asses their own personal situations as to whether the risk here is worth taking.
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