Here is the prior Phase 2a data: http://www.neurotropebioscience.com/Welcome_to_Neurotrope_BioScience/PressReleases-Mar-17-2015.html . And that essentially doesn't tell you much of anything. Patients got a single dose of the drug and there was no measurable improvement in cognition in mildly impaired patients. Not sure how that could give one confidence in the upcoming multi-dose Phase 2b data in moderate to severe patients.
Is there any strong independent data to suggest activating protein kinase C epsilon would work in AD?