Replies to post #169697 on Innovation Pharmaceuticals Inc (IPIX)

[cabel]

Much appreciated,.... thanks for sharing!

[Jhawker]

Awesome post thanks

[Pepperchino]

Excellent information, thank you!

[Phoenix300]

Your best post ever. Thanks for sharing.

Go CTIX.

[georgejjl]

More proof that AF is just trying to distort the truth.

Prurisol is a prodrug of abacavir, an old HIV drug known to cause serious hypersensitivity reactions in some patients.

https://www.thestreet.com/story/13960573/2/biotech-school-when-cellceutix-ceo-rants-about-criminal-short-smart-investors-see-red-flags.html

Cellceutix made sure that patients that could be hypersensitive to abacavir were excluded from the Prurisol trial.

Exclusion Criteria:
Positive blood test for HLA-B*5701 allele

https://clinicaltrials.gov/ct2/show/NCT02949388?term=prurisol&rank=2

"A: Prurisol TM ( abacavir (a-hydroxy)-acetate; abacavir glycolate) is a prodrug ester analog of abacavir that differs in form from ZIAGEN® (abacavir sulfate), which is a salt form of abacavir. Quite simply, it is not the same drug, but its shared similarity does allow us to leverage much of the data on ZIAGEN® in our development of Prurisol TM.

What you are referring to with respect to side effects is that ZIAGEN®has demonstrated increased risk for hypersensitivity reactions in patients who have the HLA-B*5701 allele. The risk is easily mitigated for Prurisol TM through readily available screening for the HLA-B*5701 allele and eliminating the small number of patients positive for the allele from receiving Prurisol TM. This de-risking is underscored by a nearly 2,000-patients clinical study of ZIAGEN® utilizing companion diagnostics to screen for the allele that resulted in reducing immunologically-confirmed hypersensitivity reactions to zero. We're using the same methodology.

I'll add that we're not overly concerned about diminishing the market potential due to prevalence of the HLA-B*5701 allele in psoriasis patients. During the screening for clinical studies of Prurisol TM, only about 10.5% of patients were excluded due to HLA-B*5701. Overall, there are about 7.5 million Americans with psoriasis."

http://seekingalpha.com/article/3988240-interview-new-cellceutix-president-dr-bertolino

Good luck and GOD bless,

George

[djs7]

Excellent work George. So this seems common for psoriasis trials. Thanks for giving The Truth and not The Street (AF is a manipulator).

[Hazelhurst]

Well played sir!

[sox040713]

Very nice research on the liver toxicities of other psoriasis drugs. Well done!

[Bruinfan4ever]

You should really do an SA article. You are a cheerleader and an intellectual. That is the combo needed to make the stock move.

[run256]

Many Thanks Sir !

[aculeus]

Thanks for doing that research.

[incubus-now]

Great research to again point out the scam Cramer crew.

Most medicines have side effects, and as you know, some can kill yet we take them. Seizure medicines have side effects that effect the whole body for example including eyes, mobility, liver, kidneys, muscle joint pain and damage, more. I'm sure we can go on and on with the poisons we are prescribed that effect the body but it's for a 'better good'. Statins, another poison we take to save our hearts and clear our veins while trashing our muscles, joints, liver and kidney to stay alive. When one thinks about it, we are still relatively primitive about know how to solve these mysteries.

To me it's an announcement by the Cramer short crew that they are here until the company can release new data points that destroy their narrative but by then, they will have made their money and probably gone long to take the ride back up to the real value of the stock. We'll see if they pump it when the news destroys their current narrative and intentions.