I remember someone years ago suggesting that companies like Biogen could start a Taiwan Semi type business using this expertise. This expertise probably behind many attempting biosimilars.
"for biologics sold in the US, most of the manufacturing is done in the US. "
It would be intersting to have more quantitation of this. For large companies like Genentech and Amgen, who produce a large % of biologics, its clear most of it is done in US. For smaller companies who may not have a large mfg presence, the biologics manufacturers seem to be mostly in ireland or Germany. From my experience those 2 countries constitute the bulk of contract biologic manufacturing. But i dont know the breakdown for sure.