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gestalt2

01/04/17 6:34 PM

#8798 RE: pearsby09 #8797

i'm not in the medical or scientific field - just pulling from the internet. It looks to me like some patients were one tropism and became dual tropism or were dual and went to one tropism. remember - pro 140 is for the ccr5 strain only - which is a vast majority of cases. I'm not sure but i think "finding out why" is more about patient screening and tropism changes than pro 140 function. I think Nader is more interested in making sure the trial is testing pro 140 in the correct patients and not having incorrect patients skew the data in the trial.
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jboatswain

01/04/17 8:12 PM

#8802 RE: pearsby09 #8797

I asked a similar question.. Tropism failures (low VL screening problem) does not account for why 13 patients from the 'n=28' cohort were not rolled over.

Tropism failure accounted for 5 patients. The PR was NOT even clear about whether these 5 patients come from 28 patient cohort or both cohorts.
http://www.cytodyn.com/media/press-releases/detail/204/cytodyn-concludes-phase-2b-study-with-98-success-with-4
http://www.cytodyn.com/media/press-releases/detail/144/cytodyn-announces-positive-interim-results-from-its