Replies to post #128510 on NanoViricides Inc. (NNVC)

[KMBJN]

Have you heard about EliminateDengue? I just heard about it from the book I got for Christmas, an excellent read:

"I Contain Multitudes" by Ed Yong.

https://www.amazon.com/Contain-Multitudes-Microbes-Within-Grander/dp/0062368591

Fascinating story about all the bacteria that lives in us, and how life isn't just a single organism / individual / animal, but a collection of sybmiotic organisms. Now I'm readying "The Gene" by Mukerhjee - also very interesting story about the history of genetics.

Anyways, it turns out that infecting mosquitos with Wolbachia bacteria makes the mosquitos immune to dengue, Zika, and other viruses:

http://www.eliminatedengue.com/our-research/wolbachia

http://www.nature.com/articles/srep28792

There's another company trying to introduce a more virulent strain of Wolbachia intracellular bacteria into male mosquitos such that all offspring will die. The company is named MosquitoMate:

http://mosquitomate.com/how-it-works/

http://www.nature.com/articles/srep28792

and there is intrexon as well, which genetically modifies the mosquitos.

The eliminate dengue method seems the best solution.

I also like Inovio's DNA based vaccines and DNA based antibodies, which have shown promise in both Zika and Chikungunya animal models (and Zika vaccine looks good in humans so far).