Replies to post #280180 on Avid Bioservices Inc (CDMO)

[biopharm]

Simultaneous TF expression and PS (phosphatidylserine) exposure by tumor cells promote the extravascular activation of blood coagulation.

Its becoming clearer day by day how big PS Targeting will become. The more info that comes out regarding flipped PS aka PS exposure or aka externalization of Phosphatidylserine and how it leads to high levels of MDSC's and now I am seeing in more publications like the reference above => shows a direct link to blood clots and it should make sense to everyone that blood clots are more common in cancer patients.

Why Blood Clots Are More Common With Cancer

“Blood clots are common in all cancers,” says Jacques-Pierre Fontaine, MD, a chest surgeon at Moffitt Cancer Center in Tampa, Florida. “Having lung cancer surgery increases the risk, and we routinely protect patients by giving them blood thinners after surgery.”

Having cancer increases blood clotting in ways we don’t completely understand — but "anything that increases blood clotting increases the risk for DVT and embolism,” says Dr. Raftopoulos.
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http://www.everydayhealth.com/news/link-between-lung-cancer-blood-clots/

It will be interesting who exposes themselves first in being interested in picking up PS Targeting. Peregrine knows the market cap of PPHM is extremely undervalued, to the point where any biotech stock analyst should be ashamed for not covering Peregrine more in depth.

Hey... the worst that can happen is you become a BOD somewhere : )

but seriously, now we now MD's prescribe blood thinners and two types: Anticoagulants vs Antiplatelets...

Anticoagulants: such as heparin or warfarin (also called Coumadin), work on chemical reactions in your body to lengthen the time it takes to form a blood clot. (many side effects)

Antiplatelet: drugs, such as aspirin, prevent blood cells called platelets from clumping together to form a clot. Platelets are tiny cell particles found in your blood. Under a microscope, they look like plates. When you get a cut, platelets rush to the wound. They:

Become sticky.
Bind together.
Form a clump to help stop the bleeding.

But this stickiness can also lead to blood clots, clogged arteries, heart attack or stroke.

Antiplatelets work by making your blood less sticky.

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I bet patients in PS Targeting trials that went into the trial with other indications, such as elevated blood pressure just may have some within Big Pharma scratching their heads and wondering how the hell do they implement such a PS Targeting wonder drug, when it may remove profits from other pipelines.