Replies to post #277163 on Avid Bioservices Inc (CDMO)

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"i think it's safe to say a pdl-1 drug with bavi has been tested in humans...." (Durvalumab)

"now the nccn merck trial announced in sept 2016 with a pdl-1" (PD-1) "starts as a phase 2, not a phase 1... if there were safety issues w/ bavi and pdl-1, this trial would not be starting as a phase 2 imo."

I agree. They are bypassing a P1 trial, signalling that there were no safety issues. What I am tweaking here is that they have transferred the positive safety consideration from a PD-L1 to a PD-1, Keytruda.

I find that interesting.

"sk confirms they are talking to merck...

they have all the ingredients to get a deal done now or very soon... "

IMO

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