Clear to you me and the rest of the investing public that the dosage is the issue but obviously no clear to the "professionals" putting the trial together. They are totally shooting at the hip right now and honestly don't know what the correct dosing should be. I think they just used 8mg/kg because that is as far as their study went. This is just crazy to spend this sort of money on a trial with no dose escalation built in and I don't remember if they did any PK analysis to see how long this stays in the system.