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Protector

08/08/16 6:08 AM

#269785 RE: entdoc #269771

entdoc, I think there was a companion test with Opdivo for PD-L1 responders detection.

I am sure BMY is going to be stratifying responders and non-responders on the percentage of PD-L1, yada.



If you combine with bavituximab that test may not be good anymore because the # of responders should increase. The test however would continue to yield the max 30% responders.

Maybe the test will be a filter for who can get Opdivo alone (30%) or Opdivo+Bavi (60-70%). However, that would not be a good development because the 30% would not get the other Bavi advantages of milding side effects by kicking on the immune system and they would not benefit the anti-relapse properties of Bavituximab (and Fx-gamma binding).