Replies to post #220077 on Elite Pharmaceuticals Inc (ELTP)

[rrr2003]

Tell that to Nasrat. He is the one that is claiming the technologies are very similar using his own words. Guess mgmt needs a chemistry 101 refresher according to you.

Both products use naltrexone as the opiod antagonist but Nasrat is not saying they are very similar.

"FDA advisory committee review of Pfizer’s AL-02 determined that oxycodone can be selectively extracted from intact pellets by a number of straightforward techniques and certain common solvents appear to be capable of removing naltrexone selectively from the crushed pellets. How does ELI-200 SequestOx result compare if subjected to the same criteria?

That’s a very good question. First, the most important entity in all of our work is the patient. When a patient is in pain, their primary goal and ours is to give them pain relief. Therefore, you’re going to give them a pill, whether it’s instant release or sustained release that needs to allow the drug to get out and get into their body. So, extracting a product is a foregoing conclusion. You have to be able to do that to give the pain relief effect. So, can you extract stuff with normal solvents? Yes, you drink everything with a glass of water and in due time the medicine comes out. So, this is actually standard. Can you stop that from happening? No, not only for anti abuse. If somebody want to kill themselves and they take 20 aspirins, all the aspirin will come out and it will hurt them. So, we have to be able to get the product out into the body. So, extracting Pfizer’s product with common solvent such as even water or any other product is really what you want done, okay? We don’t want something that’s so sequestered that doesn’t help you.

Now the issue becomes, how do you overcome people trying to abuse these products? There are ways you can, there are ways you can’t; this is why it’s abuse resistant not foolproof. What can you do? You can interject certain chemicals that will stop people from snorting a product or crushing it in their mouth or injecting it. Our product as well as Pfizer’s are superior when it comes to that. Any time you crush Pfizer’s product or Elite’s, the naltrexone will spill out and it will render the opioid ineffective. So, if you crush it and you snort it or you inject it, you will think it’s a placebo.

Can you, like the advisory committee member said, put in tablets and a bunch of water and once they all dissolved and then drink them? Yes, you can; you can do that with any product just about. So, I actually attended this meeting, Chris and I did. And I was very pleased with the way Dr. Hertz conducted their self with that. In that yes, we’re looking for something that’s anti abuse but it is for certain things such as injectable and insufflation. We don’t have the technology as of today for somebody or to stop somebody from taking multiple pills."



http://seekingalpha.com/article/3983163-elite-pharmaceuticals-eltp-ceo-nasrat-hakim-q4-2016-results-earnings-call-transcript?part=single