Replies to post #32078 on Biotech Values

[ghmm]

poorgradstudent,

Thanks for the reply and link. It is interesting to note that treatment-stop indicator to be highly significant to disease progression in this trial. I would think three month of chemo would have an effect of PFS, how much??

I had come across some other front-line trials with different PFS such as SCOTROC which compared paclitaxel and docetaxel (granted it was Stages IC to Stage IV) and had about 15 month PFS in each arm (I am not sure whether this is from after surgery or after chemo).

Another other study I have heard is a good reference is the GOG-0182. I haven't seen the ASCO presentation of this. The company pointed out in a presentation that study goes from time of randomization so it would include the chemo time (6 months or so).