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Mean Weimaraner

06/10/16 7:51 AM

#5890 RE: sirglenn #5889

Not sure where you heard that but this is likely how it'd apply. "The heart of the Antigen Express technology platform is the Ii (invariant chain) protein, which regulates antigen presentation by MHC class II molecules and consequent T helper cell activation. We have established two technology platforms and advanced a number of product-focused projects toward the clinic based on the modulation of expression and use of the Ii protein. The first of these technologies involves suppression of expression of the Ii protein while the second involves the design of Ii 'hybrids', which contain both an MHC class II antigenic epitope and a portion of the Ii protein."