"Oxycodone can be selectively extracted from intact pellets by a number of straightforward techniques and certain common solvents appear to be capable of removing naltrexone selectively from crushed pellets, the review said."
A lot more than that. $ELTP ADFs can go to at least 50 mg Naltrexone, as per $ELTP Patents, if the FDA wants. $ELTP ADFs 2-beads are solidly stable.
FDA has not given a PDUFA for ALO-02. Stability of Pfizer's ALO-01 still very much in question. Pfizer ALO-01 would be easily abused as the 100 mg Morphine would easily mask the 4 mg Naltrexone when abused
It will be interesting what the ADCOM meeting decides for ALO-02 !
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