Replies to post #266047 on Avid Bioservices Inc (CDMO)

[JJ1223]

Thanks for your post newbieee. It is easy to forget that cancer mutates and is not an easy foe.

[JJ1223]

Here's an example of a drug that failed in its first phase 3 trial and went on to get approved to treat several cancer indications. Oh yeah, it also has about 60 billion in sales.

Clearly Avastin was not an immediate success, but the good Dr. does not give up easily.

Dr. Garnick was formerly the senior vice president of regulatory, quality and compliance at Genentech. During his 24-year career at Genentech, he was responsible for 17 new product approvals including most of the company's top selling monoclonal antibody therapeutics such as Rituxan(R), Herceptin(R), Avastin(R) and Lucentis(R).

[geocappy1]

See failure as in Big Pharma vs. Little biotech. The rules are different. That is why PPHM should have partner at whatever cost to get something approved and then worry about hitting home run. Especially when they knew they had BBs coming online soon. Not very smart.

[vinmantoo]

Here's an example of a drug that failed in its first phase 3 trial and went on to get approved to treat several cancer indications. Oh yeah, it also has about 60 billion in sales.

How about making a list of all drugs that failed in multiple clinical trials and then went on to be approved and make a ton of money? That would be a better comparison for Bavi since it has failed in multiple trials.

[lemmy]

An insult to Genentech, this implied comparison to PPHM.