Replies to post #966 on Alaunos Therapeutics Inc (TCRT)

[blackcat]

I think he's at 4+ years of survival now. Amazing in itself.

Don't know if you are familiar with the 60 minutes show on "breakthrough" status drug from polio virus.

http://www.cbsnews.com/news/promising-duke-university-polio-brain-cancer-trial-given-breakthrough-status-60-minutes/

Although this method has some promise, obviously, it has one very major drawback. It is not reversible. Should it cause too much inflammation, the patient will die. Of the 22 patients who have received it 11 are deceased. Some would be, anyway, no doubt, but that is still a high percentage and their end QOL was not good.

Simply stopping the IL-12 for a few days will completely reverse any SAEs.