Jazz, are you BOT's official interpreter?
IMO, the only things you are hearing are assumptions and conclusions based on speculation from back room broker chat.
I listened to the CC, and SK said coinfection is an option the company is considering. That's it nothing more. For you and anyone else here to make the assumption that PPHM is enrolling HIV patients in this repeat dose study is simply WRONG! I believe Dr. Godofsky and Dr. Lawitz understand the significance of not treating patients with HIV, these doctors have qualified nurses and clinicians who are trained and understand the reasons for not subjecting HIV infected patients to Bavi at this time. I am sure these principal investigators are not going to allow someone enter the study who hasn't had a recent HIV test. Before an investigational HCV drug can be tested on coinfected individuals it must prove safety and efficacy FIRST, which is the OBJECTIVE of this study. Do you have any idea of how the data from this study may be misconstrued, tossed out, how the results may be interpreted etc....if what you think is true.....
There is absolutely nothing wrong with the protocol design, it states no KNOWN HIV. Period. Way too much is being speculated and misterpreted here because the trial design is not dotted with an "I".....
Has it occurred to you that perhaps if the participant hasn't had an HIV test in the past six months documented then the PI's DONT WANT YOU? Just because PPHM isn't paying for an HIV test, does not mean they are enrolling HIV patients.....there are a lot of non-responders out there.....
You guys can speculate and dream about HIV patients slipping into this study all you want....I want NO PART OF IT, and will maintain it's simply WISHFUL THINKING on your behalf. You are entitled to your opinion as am I, and I say there will be NO HIV patients in this study. I'm not happy, no, actually LIVID that there is this type of speculation and idle chat going on regarding this protocol, when this company has the top PI's in the nation working with this compound. If they were treating ACUTE HIV, then the INCLUSION data would state so.....correct????????
+++GILD and all other of your referenced companies ain't throwing mabs at HIV!.... (who else is?).
Tanox.
+++(another reason to go after coinfection first, besides the fact that nobody else can).
Wrong. HCV advocates are hopeful that IDIX's and VRTX's HCV drugs will eventually be tested for coinfection ONCE they have proven safety and efficacy.
+++Bigon did nothing to insinuate that. Read the trial inclusion/exclusion criteria again.
Implying PPHM is letting HIV patients slip into this study because they are not paying for an HIV test is INSINUATION in my book. I did read it and I understand what KNOWN HIV infection means, and clearly understand why HIV patients CANNOT be allowed in this study. Do you?
I'm not even going to touch the DUKE issue.
JMHO....and Regards....
katie....
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