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KMBJN

02/09/16 10:08 AM

#7420 RE: TRUISM #7412

This part is untrue, isn't it?

"But the implant users ended up taking more medication overall than the daily drug users, pharmacologist Tracy Rupp of the National Center for Health Research testified, in a critique. That’s likely because it might take up to four weeks for the implant’s medication to kick in, she said, and the patients required extra medication until that happened. "

90% LESS buprenorphine tablets were used in the probuphine arm, from what I recall.

The PK data I'm remembering doesn't show a 4 week rising curve (it doesn't take 4 weeks to "kick in," even though I think even someone on the FDA panel repeated this). Doesn't it start HIGH, then settle down to its final steady state?

I really disklike misinformation / people that don't accurately report the TRUTH.