Of course we don't really know if it works on Dengue, yet.
Yep,... therein lies at least a large part of the problem with a 'shift' to Zika. There are a few significant hurdles that would have to be dealt with first.
1) As TOX testing hasn't been completed for any of NNVC's candidate drugs,.... even though they are extremely unlikely to be toxic,... it would limit acceptance of them as a curative even if a DengueCide candidate did work on Zika.
2) NNVC still can only make ~500 g batches of any of it's 'Cides at present. And even IF they could push through and get syntheses up to ~1 Kg (a reported next step in production scale-up),.... is a Kg enough to treat all the potentially sick people?
3) And even though at least report, Dr. Harris' Lab at Berkeley found that some of the DengueCide candidate compounds worked pretty darned well in an animal model against Dengue,... it hasn't been tested in Humans against anything.
If the surface binding proteins of Zika are similar enough to the ones that Dengue uses to gain entry into cells,.... it could work. But there's a whole lot of steps that would have to be taken first to make NNVC a viable "player" against the current Zika problem.
Maybe a couple years down the line,... much like getting a good vaccine in place. But not currently.
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