frog,
If I may:
"What are the possible sets of circumstances that might lead a competitive multi-national pharmaceutical company to relinquish it's license for a 'slam dunk' multi-billion dollar drug?"
They learned it wasn't slam-dunk after all. In fact they could do nothing with it.
"Next step. Of those sets of circumstances, which ones would prevent one of it's multi-national competitors from snapping up the license immediately it became available?"
Easy: If they can't do anything with it, we sure can't.
"What circumstances can be conceived that prevented all of the potential players in the global pharmaceutical business from entering into a bidding war to obtain said 'slam dunk' muti-billion dollar drug?"
Beth Israel didn't want a bidding war. They negotiated with someone who they have faith in being able to complete the project.
Too, friendships, prior relationships count with some people.
Of course, most of the above assumes there ever was a prior licensee. It's obvious you think there was, and judging from your comments, you must have been privy to the entire matter.