Replies to post #97640 on Kraig Biocraft Laboratories Inc (KBLB)

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Safety Assessment Of Silk Proteins As Used In Cosmetics
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Status: Scientific Literature Review for Public Comment
Release Date: March 2, 2015
Panel Date: June 15-16, 2015


INTRODUCTION

The safety of the following 10 silk proteins as used in cosmetics is reviewed in this safety assessment:

* Fibroin
* Hydrolyzed Fibroin
* Hydrolyzed Sericin
* Hydrolyzed Silk
* MEA-Hydrolyzed Silk
* Sericin
* Silk
* Silk Extract
* Silk Powder
* Silkworm Cocoon Extract

These ingredients function as skin and hair conditioning agents and bulking agents in cosmetic products.1

Silk is a fibrous protein that is a product of insects that belong to the Lepidoptera order. The silks that have been most extensively characterized are from the domesticated silk worm, Bombyx mori, and from spiders (Nephila clavipes and Araneus diadematus). Silk proteins are usually produced within specialized glands.

These proteins are biosynthesized in epithelial cells and secreted into the lumen of these glands, where the proteins are stored prior to being spun into silk fibers by the silk-producing animal.2




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