Replies to post #2250 on Insmed Inc (INSM)

[Christiaan F]

The Insulin-Like Growth Factor System and Its Pleiotropic Functions in Brain
V. C. Russo, P. D. Gluckman, E. L. Feldman and G. A. Werther [/]

Actually the last study you are citing, concerning brain development & rhIGF-1 is also presented at ESPE 2006:


Saturday, July 01, 2006
Session: Clinical Focus 1 - GH/IGF treatment (Click here for session schedule)
Date: Saturday, July 01, 2006
Time: 12:00 - 13:00
Room: Willem Burger Zaal
Moderator: Bessie E. Spiliotis, Patras, Greece
Moderator: Gerhard Binder, Tübingen, Germany
Save session to Outlook calendar
Remove from Planner Partial IGF-I deficiency demonstrates the critical role of IGF-I in growth and brain development
Netchine, Irène (presenting); Azzi, Salah; Houang, Muriel; Seurin, Danielle; Daubas, Claudine; Ricort , Jean-Marc; Legay , Christine; Perin, Laurence; Heirich, Robert; Godeau, François; Le Bouc, Yves
France

CF1-95
Monday, July 03, 2006
Session: Poster Session 3 - IGF / IGFBP (Click here for session schedule)
Date: Monday, July 03, 2006
Time: 13:45 - 14:45
Room: Expo Hall
Moderator: Ragnar Bjarnasson, Reykjavik, Iceland
Save session to Outlook calendar
Remove from Planner Comparative catch-up growth of height, foot and brain in children with Laron syndrome (LS) treated by IGF-1 to that of children with IGHD treated by HGH
Silbergeld, Aviva; Lilos, Pnina; Laron, Zvi (presenting)
Israel
PO3-610

CF

[rstor1]

Thanks for the links. I had not seen them.

I suppose that it should not be surprising that IGF-1 and the binding proteins are involved in growth/protection of nerve cells.

This is truly a franchise hormone. The question now becomes one of establishing/protecting the IP as new applications are developed.

Regards,
Bob