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stockhlder101

06/18/06 6:10 AM

#46749 RE: Gcbr #46744

Biofrontera's products demonstrate high success rates:

BF-200 ALA for actinic keratosis
Status: Phase IIb/III clinical trial

The design of the ongoing clinical study includes an exploratory dose finding phase with 80 patients treated with doses of 1, 3 and 10% ALA. The second part of the study is the confirmatory phase III tested on 40 placebo and 120 verum patients. The clinical trial is randomized, placebo-controlled and takes place in 13 centers in Germany. Excellent clinical efficacy of BF-200 ALA has already been demonstrated in two earlier clinical trials for superficial basal cell carcinoma, where a single treatment abolished more than 80 % of the tumors.

BF-200 ALA for condyloma
Status: Phase IIb/III clinical trial

Two phase II trials have been performed with condyloma and vulvar intraepithelial neoplasia III. Even as late as 6 months after a single treatment with BF-200 ALA 60-70 % of the lesions were completely, the remainder partially remitted.

BF-derm1 for antihistamine-refractory urticaria
Status: Phase II clinical trial

The ongoing clinical study is a phase II randomized, double blind, placebo-controlled parallel study with an adaptive design in five clinical centers. Eight weeks of treatment with oral doses of 100mg, 200mg, 300mg or placebo are tested on male and female patients with severe chronic urticaria, aged 18-75 years. The primary endpoint of the study is an improvement of the urticaria symptoms as assessed by the urticaria-activity scale (UAS). In a first interim report, the study indicated an UAS improvement of 30-40 % over placebo without clinically relevant drug-induced side-effects. Treatment of the second group of patients has been completed, the data are currently under evaluation

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dr frudaky

06/18/06 7:42 AM

#46753 RE: Gcbr #46744

Gcbr


Thank you for that link from your continuing dd efforts to pump up the value of this stock. Unfortunately, that little bit of news was dated November 2, 2004, and apparently totally dismissed as being of no consequence by prospective investors, given the fact the pps thereafter promptly plummeted to the present equivalent of a pre first r/s subsubpenny .000875. Are you currently still buying any more shares for "insurance", as you said you had done when the pps first dropped to subpenny? Just curious.

Thanks anyway, but please keep on trying and maybe, just maybe, one day you will finally ring that bell or catch that golden ring! LOL!

On a more serious note, I was hoping this investment would make me enough money so that I too might be able to buy a trailer to play in....just like the one you are always bragging about. Alas, the prospect for that has pretty much faded for me and, I suspect, anyone else here having a similar lofty aspiration, given the condition of this investment.

JMHO and have a very happy day!

dr f