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hutschi

08/16/15 1:32 PM

#230430 RE: biopharm #230426

Dropped out means no more Docetaxel, what else would they get then? No more HOPE for them?

.....I guess they can just drop out of the trial saying that they don't like the side affects and I wonder how many ask to be dropped out based on if they are in the Bavi+Docetaxel arm vs the Docetaxel+placebo arm ?


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2ndstr2thert

08/16/15 4:14 PM

#230440 RE: biopharm #230426

I do not understand why reducing MDSC'S is a good thing. It is my understanding that when MDSC'S are attached to bavi which in turn are attached to PS that this coupling enables the MDSC'S to foster an M1 state. One of the reasons Docetaxel is used with bavi is to ellicit PS. Why illicit PS unless there is a way to use it to produce a positive result ?