Here here TOB ... K efficacy signals at this stage, Ph I, is HUGE.
Below, an excerpt from an earlier post of mine - link to a study that shows recent cancer drug approvals data -- how low/high the bar is as to PFS and OS across various cancers.
Based on today's tidbits as to K efficacy, and if results hold/improve across future K trials, well, vis a vis this comparative efficacy data, Kevetrin would have a great shot at getting approved.
Wouldn't be surprised if Breakthrough Therapy designation is the the next feather in its cap.
have not had the chance to look back over the ASCO report to see about the timing of doses but I would guess that there is at least a couple of 750 mg ovarian CA patients who have had 3 month scans, but maybe not 6 month scans
But I do not know
Do you know the cohort dates?
I could not agree more that some response at lower doses is EXCELLENT
It is amazing to think that patients treated with a drug with a 2 hour half life once weekly on 3 occasions would have any tumor stabilization, especially since those patients have already been through all the usual care with progression of disease