RCJ, I don't think CK would just plainly lie about this. Nothing to gain.
But in a possible scenario that I suggested (SPECULATION) he would be telling the trued.
A) DMC writes letter to PPHM, advice early STOP
B) PPHM says, no...let trial mature
C) 1st lookin-criteria are NOT met (1/3 events)
D) ...at this point it is FAIR to say 1st look-in did NOT take place
PPHM however now knows that the results are good because of (A) and because of (B) they can now say that as long as the 1st look-in doesn't occur patients are alive because since they now the total #enrolled and evented (as exwannebe explained) and since they have (A) results are getting better the longer it takes for (C) to occur. And they are NOT lying under application of (D) but can PREPARE everything.
What is more, under that scenario PPHM can virtually PLAN its EOT because they only have to take the DMC advice and stop when they want. And personally I think they should wait untill EVERYTHING they can do to be ready is done (CT MOS evolves in their advantage under these circumstances and a super result may help getting lower patients number requirements in other trials).
Last but not least, which such cards in the hand they could negotiated a partnership for Europe as if they have SUNRISE approved (no milestones, just the conditions as if it was approved and sign the day the FDA letter arrives or put a conditional activation clause in the contract).
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