PharmaCyte Biotech has achieved compelling results with this targeted chemotherapy approach too.
In a phase 1/2 trial examining the benefit of the Cell-in-a-Box delivery of ifosfamide versus the results gemcitabine would be able to achieve alone, the Cell-in-a-Box approach improved the median survival time from 28 to 44 weeks. Equally impressive is the fact that the number of one-year survivors increased from 18 percent to 36 percent of the study's patients. Even more encouraging are the lack of side effects witnessed with the lower doses of ifosfamide that are used in this approach.
The company reports it's aiming to begin phase 2b clinical trials of Cell-in-a-Box in conjunction with low doses of ifosfamide in Australia sometime in the third quarter of this year, which will compare it to the combination of Abraxane plus gemcitabine.
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