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ash111

05/13/15 1:47 PM

#7243 RE: LasNubes #7242

TPIV "Over the past year, we have significantly strengthened our balance sheet by raising additional working capital and reducing our stockholders’ deficit from $8.7 million in December 2013 to $2.46 million in the second quarter and further down to $656,000 in the third quarter. On August 14, 2014, we closed a $2 million registered direct offering with a fundamental institutional investor and a further $2.5 million in the first quarter of 2015, giving us confidence in our ability to continue developing our products on the path to commercialization. The strength of our science and development approaches is becoming more widely appreciated, particularly as our clinical program has now generated positive interim data on both clinical programs in Breast and Ovarian Cancer. Also, we are pleased to report that all our pre-clinical programs are seeing positive outcomes.

With the new funding the Company is focusing on the following key initiatives:

Entry into Phase II HER2/neu Breast Cancer Trials

Entry into Phase II Triple Negative Cancer Trials and Fast Track & Orphan Drug Status

Produce new PolyStart ™ constructs, in-house, to facilitate collaborative efforts in our current clinical indications and those where others have already indicated interest in combination therapies."