Replies to post #100346 on Innovation Pharmaceuticals Inc (IPIX)

[F1ash]

http://www.arvo.org/webs/am2015/abstract/111.pdf


"BRI reduced CFU in abraded corneas significantly
more than intact corneas (P<0.05, M-W) suggesting the corneal
epithelium acts as a barrier for penetration. There was no difference in CFU in abraded and intact corneas with VAN (P>0.05, M-W) suggesting high penetration through the corneal epithelium.
Conclusions: BRI demonstrated broad spectrum in vitro activity
against ocular pathogens. BRI was equally efficacious as VAN in
a MRSA keratitis model only when the corneal epithelium was
removed."